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The PK-Eye: A Novel In Vitro Ocular Flow Model for Use in Preclinical Drug Development

“A 2-compartment in vitro eye flow model was developed to estimate ocular drug clearance by the anterior aqueous outflow pathway. The model is designed to accelerate the development of longer-acting ophthalmic therapeutics.” 

 

The PK-Eye: A Novel In Vitro Ocular Flow Model for Use in Preclinical Drug Development

Awwad S, Lockwood A, Brocchini S, Khaw PT.

Development of an in vitro model to estimate mass transfer from the anterior cavity.

Liu, T.; Ibeanu, N.; Brocchini, S.; Khaw, P.T.; Bouremel, Y.; Awwad, S. 

Antibody loaded collapsible hyaluronic acid hydrogels for intraocular delivery

Egbu R, Brocchini S, Khaw PT, Awwad S.

Electrospun formulations of acyclovir, ciprofloxacin and cyanocobalamin for ocular drug delivery

Baskakova A, Awwad S, Jiménez JQ, et al.

Flow Hydrodynamics and Eye Movements on Intraocular Drug Clearance

Velentza-Almpani, A.; Ibeanu, N.; Liu, T.; Redhead, C.; Khaw, P.T.; Brocchini, S.; Awwad, S.; Bouremel, Y.

Real-Time Monitoring Platform for Ocular Drug Delivery

Awwad, S.; Ibeanu, N.; Liu, T.; Velentza-Almpani, A.; Chouhan, N.; Vlatakis, S.; Khaw, P.T.; Brocchini, S.; Bouremel, Y. 

Comparative Study of In Situ Loaded Antibody and PEG-Fab NIPAAM Gels

Awwad S, Al-Shohani A, Khaw PT, Brocchini S.

Comparative Study of In Situ Loaded Antibody and PEG-Fab NIPAAM Gels

Sustained release ophthalmic dexamethasone: In vitro in vivo correlations derived from the PK-Eye

Awwad S, Day RM, Khaw PT, Brocchini S, Fadda HM.

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